Diffusion MRI (dMRI) applications are growing rapidly in diagnostic and treatment, but its potential role in bone imaging is not fully established yet due to difficulties in implementation of dMRI in human bone assessment. Since dMRI can capture early alterations of tissue microstructure, it could become a superior method in assessing different aspects of bone quality. Bone quality represents a wide range of features like bone microstructure and also is associated with bone strength. This paper discusses considerations and challenges of dMRI in bone imaging, current status, and suggestions for development of dMRI in research studies and clinics.
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Author: Ms. Mahsa Talebi