Cortical bone MRI is a novel field which is introducing new aspects of bone quality assessment. Short echo time (STE) pulse sequences are able to capture the signal of cortical bone free water residing in microscopic pores. The Authors of this study quantified cortical free water content employing STE-MRI and validated their measurements using dehydration experiment. Then, they quantified free water content and T1 in 30 healthy subjects. They found significant correlation between cortical free water components and age. This study elucidates the possible role of cortical bone water components in bone quality assessment.
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Author: Ms. Mahsa Talebi