Single STE-MR Acquisition in MR-based Attenuation Correction of Brain PET Imaging Employing a Fully Automated and Reproducible Level-set Segmentation Approach

 

Abstract

 

Objective:

The aim of this study is to introduce a fully automatic and reproducible short echo-time (STE) magnetic resonance imaging (MRI) segmentation approach for MR-based attenuation correction of positron emission tomography (PET) data in head region.

Results:

The proposed segmentation method returned accuracy and specificity values of over 90 % for cortical bone, air, and soft tissue regions. The MR- and CT-derived μ-maps were compared by quantitative histogram analysis.

Keywords:

PET/MRI, Attenuation correction, Attenuation map, STE-MRI, Level-set technique .
Authors:

A Fathi Kazerooni, M Ay, S Arfaie, P Khateri, and H Saligheh Rad .
Journal:

Molecular Imaging and Biology
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