Single STE-MR Acquisition in MR-based Attenuation Correction of Brain PET Imaging Employing a Fully Automated and Reproducible Level-set Segmentation Approach

Abstract

Objective: The aim of this study is to introduce a fully automatic and reproducible short echo-time (STE) magnetic resonance imaging (MRI) segmentation approach for MR-based attenuation correction of positron emission tomography (PET) data in head region.
Results: The proposed segmentation method returned accuracy and specificity values of over 90 % for cortical bone, air, and soft tissue regions. The MR- and CT-derived μ-maps were compared by quantitative histogram analysis.